Table 4. Independent prognostic factor for OS and DFS by multivariate Cox regression analysis for the entire cohort of patients (n = 428).

Variable	OS		DFS
	HR (95%CI) p		HR (95%CI) p
nLNs		0.000		0.001
0	1		1
1–7	0.489(0.245–0.977)		0.632(0.337–1.184)
>7	0.206(0.106–0.403)		0.366(0.201–0.668)
Pathological stage	2.000(1.165–3.435)	0.012	1.647(1.050–2.581)	0.030
Tumor size (cm)*	1.867(1.085–3.212)	0.024	1.587(1.042–2.417)	0.031
Visceral pleuralinvasion	1.841(1.189–2.851)	0.006	NS
Age*	NS		1.568(1.110–2.214)	0.011
Chemotherapy	NS		1.483(1.041–2.112)	0.029

OS, overall survival; DFS, disease-free survival; HR, hazard ratio; 95% CI, 95% confidence interval; p, p-value; NS, not significant; nLNs, the number of resected lymph nodes;

^*variables, considering 65 as age cutoff and 3.5cm as cutoff for nLNs.