Table 2. Univariate a Predictors of Cord and Three Year DNA Methylation (categorical).
| Cord DNA Methylation (ng/100ng total DNA) | Cord and Three Year DNA Methylation (ng/100ng total DNA) | |||||||||
| Cord (subset) b | Three Year | |||||||||
| N | % | Mean | SD | N | % | Mean | SD | Mean | SD | |
| Maternal Education | ||||||||||
| <HS | 100 | 36.0 | 1.03 | 1.12 | 55 | 33.3 | 0.90 | 1.17 | 1.48 | 1.16 |
| HS | 96 | 34.5 | 1.17 | 1.12 | 67 | 40.6 | 1.18 | 1.15 | 1.87 | 1.15 |
| >HS | 82 | 29.5 | 1.20 | 1.13 | 43 | 26.1 | 1.00 | 1.20 | 1.22 | 1.19 |
| Marital Status | ||||||||||
| Married/Cohab. | 206 | 75.2 | 1.04 | 1.15 | 119 | 73.0 | 0.94 | 1.19 | 1.56 | 1.19 |
| Unmarried | 68 | 24.8 | 1.15 | 1.08 | 44 | 27.0 | 1.05 | 1.11 | 1.52 | 1.11 |
| Material Hardship | ||||||||||
| No | 159 | 57.0 | 1.07 | 1.09 | 93 | 56.4 | 0.97 | 1.13 | 1.60 | 1.12 |
| Yes | 120 | 43.0 | 1.21 | 1.11 | 72 | 43.6 | 1.13 | 1.15 | 1.48 | 1.14 |
| Public Assistance | ||||||||||
| No | 23 | 8.3 | 1.14 | 1.26 | 10 | 6.1 | 1.60 | 1.45 | 1.58 | 1.43 |
| Yes | 255 | 91.7 | 1.12 | 1.07 | 155 | 93.9 | 1.00 | 1.10 | 1.54 | 1.09 |
| Ethnicity | ||||||||||
| Dominican | 193 | 69.2 | 1.16 | 1.08 | 111 | 67.3 | 1.06 | 1.12 | 1.68 | 1.11 |
| African American | 86 | 30.8 | 1.06 | 1.13 | 54 | 32.7 | 0.98 | 1.17 | 1.30 | 1.17 |
| BMI | ||||||||||
| Underweight | 14 | 5.0 | 1.19 | 1.35 | 9 | 5.5 | 1.05 | 1.47 | 1.49 | 1.43 |
| Normal weight | 125 | 44.8 | 1.28 | 1.10 | 74 | 44.8 | 1.31 | 1.14 | 2.01 | 1.13 |
| Overweight | 62 | 22.2 | 0.97 | 1.15 | 40 | 24.2 | 0.84 | 1.20 | 1.85 | 1.18 |
| Obese | 78 | 28.0 | 1.02 | 1.13 | 42 | 25.5 | 0.82 | 1.20 | 0.83 | 1.18 |
| Nulliparous | ||||||||||
| No | 137 | 49.5 | 1.21 | 1.10 | 79 | 48.17 | 1.16 | 1.14 | 1.68 | 1.14 |
| Yes | 140 | 50.5 | 1.04 | 1.10 | 85 | 51.83 | 0.91 | 1.14 | 1.42 | 1.13 |
| Former smoker | ||||||||||
| No | 212 | 81.9 | 1.12 | 1.08 | 126 | 82.9 | 1.07 | 1.11 | 1.78 | 1.11 |
| Yes | 47 | 18.1 | 1.18 | 1.18 | 26 | 17.1 | 0.85 | 1.26 | 1.00 | 1.25 |
| ETS | ||||||||||
| No | 181 | 66.1 | 1.11 | 1.09 | 104 | 64.2 | 0.99 | 1.12 | 1.63 | 1.12 |
| Yes | 93 | 33.9 | 1.15 | 1.12 | 58 | 35.8 | 1.12 | 1.17 | 1.46 | 1.16 |
| Sex | ||||||||||
| Male | 130 | 46.6 | 1.14 | 1.10 | 78 | 47.3 | 0.96 | 1.14 | 1.50 | 1.14 |
| Female | 149 | 53.4 | 1.12 | 1.10 | 87 | 52.7 | 1.10 | 1.13 | 1.59 | 1.13 |
Univariate a Categorical Predictors of Cord and Three Year DNA Methylation, geometric mean and SD.
a
Analyses corrected for inter-plate variation.
b
The ‘subset’ includes children who have contributed both cord and three year DNA samples.
Abbreviations: Yr (year); HS (High School); BMI (Body Mass Index); ETS (Environmental Tobacco Smoke).