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. 2013 Sep 4;8(9):e72824. doi: 10.1371/journal.pone.0072824

Table 3. Univariate a Predictors of Cord and Three Year DNA Methylation (continuous).

Cord DNA Methylation (ng/100ng total DNA) Cord DNA Methylation (subset)b (ng/100ng total DNA) Three Yr DNA Methylation (ng/100ng total DNA)
N Statistical estimate p- value N Statistical estimate p-value Statistical estimate p-value
Maternal Ht 277 beta −0.003 0.889 165 beta 0.020 0.487 −0.035 0.194
rho −0.018 0.770 rho 0.045 0.570 −0.066 0.400
Pre-preg. Wt. 270 beta −0.004 0.018 159 beta −0.005 0.055 −0.009 0.000
rho −0.125 0.040 rho −0.199 0.012 −0.315 0.000
Pre-preg. BMI 269 beta −0.023 0.029 159 beta −0.033 0.027 −0.049 0.000
rho −0.124 0.043 rho −0.234 0.003 −0.293 0.000
Weight gain 252 beta 0.003 0.433 152 beta 0.007 0.265 0.000 0.986
rho 0.050 0.434 rho 0.037 0.651 −0.086 0.293
Maternal age 279 beta −0.005 0.743 165 beta −0.023 0.229 −0.038 0.040
rho −0.040 0.502 rho −0.184 0.018 −0.176 0.023
Total PAH 268 beta 0.076 0.361 159 beta 0.080 0.524 −0.067 0.576
rho −0.03 0.66 rho 0.076 0.344 −0.095 0.235

Univariate a Continuous Predictors of Log-transformed Cord and Three Year DNA Methylation, Beta and Correlation Coefficients.

a

Regression analyses corrected for inter-plate variation.

b

The ‘subset’ includes children who have contributed both cord and three year DNA samples.

Abbreviations: Yr (year); Ht (height); Wt (weight); BMI (Body Mass Index); PAH (Polycyclic Aromatic Hydrocarbons).