Table 3. Univariate and multivariate analyses of current hospitalisation-related factors associated with a CTX-M-producing ST131 or non-ST131 E. coli clinical isolate.
Univariate analysis | Multivariate analysis | |||||
Characteristic | ST131 (n = 55) | Non-ST131 (n = 97) | Odds ratio | P value | Odds ratio | P value |
No. (%) | No. (%) | (95% CI) | (95% CI) | |||
Transferred from another hospital | 32 (25.5) | 18 (18.6) | 1.5 (0.7–3.3) | 0.3 | ||
Mc Cabe score 2 | 11 (21.6) | 23 (27.1) | 0.7 (0.3–1.7) | 0.5 | ||
Immunocompromised | 15 (27.3) | 36 (37.1) | 0.6 (0.3–1.3) | 0.2 | ||
Between admission and inclusion | ||||||
- Ward | ||||||
• ICU | 4 (7.3) | 27 (27.8) | 0.3 (0.1–0.9) | 0.2 (0.05–0.8) | 0.02 | |
• LTCF | 21 (38.2) | 14 (14.4) | 2.8 (1.2–6.3) | 0.0009* | 4.4 (1.3–14.7) | 0.02 |
• Others | 30 (54.5) | 56 (57.8) | 1 | 1 | ||
- Invasive device during the last week | 33 (60.0) | 84 (86.6) | 0.2 (0.1–0.5) | 0.0003 | ||
• urine drainage | 11 (20.0) | 45 (46.4) | 0.3 (0.1–0.6) | 0.002 | ||
• mechanical ventilation | 5 (10.6) | 19 (20.0) | 0.5 (0.2–1.4) | 0.2 | ||
• intravascular devices | 31 (56.4) | 81 (84.4) | 0.2 (0.1–0.5) | 0.0003 | ||
- Antibiotic receipt | 24 (43.6) | 57 (58.8) | 0.5 (0.3–1.1) | 0.07 | ||
• cotrimoxazole | 3 (5.5) | 6 (6.2) | 0.9 (0.2–3.6) | 0.9 | ||
• fluoroquinolones | 7 (12.7) | 10 (10.3) | 1.3 (0.5–3.5) | 0.7 | ||
• penicillins | 10 (18.2) | 26 (26.8) | 0.6 (0.3–1.4) | 0.2 | ||
• extended spectrum cephalosporins | 6 (10.9) | 12 (12.4) | 0.9 (0.3–2.5) | 0.8 | ||
• aminoglycosides | 2 (3.6) | 11 (11.3) | 0.3 (0.06–1.4) | 0.1 | ||
• carbapenems | 1 (1.8) | 8 (8.3) | 0.2 (0.03–1.7) | 0.14 | ||
• ≥5 days | 13 (23.6) | 35 (36.1) | 0.5 (0.3–1.2) | 0.1 | ||
Specimen and infection data | ||||||
- specimen sampled after 48 h of hospitalisation | 35 (63.6) | 51 (52.6) | 1.6 (0.8–3.1) | 0.2 | ||
- specimen sampled after >10 days of hospitalisation | 21 (38.2) | 35 (36.1) | 1.1 (0.6–2.2) | 0.8 | ||
- urine sample | 39 (70.9) | 58 (59.8) | 1.6 (0.8–3.3) | 0.2 | ||
- urinary tract infection | 42 (76.4) | 58 (59.8) | 2.2 (1.0–4.6) | 0.04 |
ICU; intensive care unit, LCTF; long term care facility,
P value resulting from the analysis of the variable “ward” classified into 3 categories, ie ICU, LCTF and others.