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. 2013 Sep 4;8(9):e72191. doi: 10.1371/journal.pone.0072191

Table 3. Univariate and multivariate analyses of current hospitalisation-related factors associated with a CTX-M-producing ST131 or non-ST131 E. coli clinical isolate.

Univariate analysis Multivariate analysis
Characteristic ST131 (n = 55) Non-ST131 (n = 97) Odds ratio P value Odds ratio P value
No. (%) No. (%) (95% CI) (95% CI)
Transferred from another hospital 32 (25.5) 18 (18.6) 1.5 (0.7–3.3) 0.3
Mc Cabe score 2 11 (21.6) 23 (27.1) 0.7 (0.3–1.7) 0.5
Immunocompromised 15 (27.3) 36 (37.1) 0.6 (0.3–1.3) 0.2
Between admission and inclusion
- Ward
• ICU 4 (7.3) 27 (27.8) 0.3 (0.1–0.9) 0.2 (0.05–0.8) 0.02
• LTCF 21 (38.2) 14 (14.4) 2.8 (1.2–6.3) 0.0009* 4.4 (1.3–14.7) 0.02
• Others 30 (54.5) 56 (57.8) 1 1
- Invasive device during the last week 33 (60.0) 84 (86.6) 0.2 (0.1–0.5) 0.0003
• urine drainage 11 (20.0) 45 (46.4) 0.3 (0.1–0.6) 0.002
• mechanical ventilation 5 (10.6) 19 (20.0) 0.5 (0.2–1.4) 0.2
• intravascular devices 31 (56.4) 81 (84.4) 0.2 (0.1–0.5) 0.0003
- Antibiotic receipt 24 (43.6) 57 (58.8) 0.5 (0.3–1.1) 0.07
• cotrimoxazole 3 (5.5) 6 (6.2) 0.9 (0.2–3.6) 0.9
• fluoroquinolones 7 (12.7) 10 (10.3) 1.3 (0.5–3.5) 0.7
• penicillins 10 (18.2) 26 (26.8) 0.6 (0.3–1.4) 0.2
• extended spectrum cephalosporins 6 (10.9) 12 (12.4) 0.9 (0.3–2.5) 0.8
• aminoglycosides 2 (3.6) 11 (11.3) 0.3 (0.06–1.4) 0.1
• carbapenems 1 (1.8) 8 (8.3) 0.2 (0.03–1.7) 0.14
• ≥5 days 13 (23.6) 35 (36.1) 0.5 (0.3–1.2) 0.1
Specimen and infection data
- specimen sampled after 48 h of hospitalisation 35 (63.6) 51 (52.6) 1.6 (0.8–3.1) 0.2
- specimen sampled after >10 days of hospitalisation 21 (38.2) 35 (36.1) 1.1 (0.6–2.2) 0.8
- urine sample 39 (70.9) 58 (59.8) 1.6 (0.8–3.3) 0.2
- urinary tract infection 42 (76.4) 58 (59.8) 2.2 (1.0–4.6) 0.04

ICU; intensive care unit, LCTF; long term care facility,

*

P value resulting from the analysis of the variable “ward” classified into 3 categories, ie ICU, LCTF and others.