Table 2.
Mean FA (x1000) Values for Patients and Healthy Volunteers 1
| Adjusted Confidence Intervals of Difference Between Groups 2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| SZ N = 35 |
BP N = 20 |
HC N = 56 |
HC - SZ | HC - BP | SZ - BP | ||||
| Mean (SD) | Mean (SD) | Mean (SD) | 95% CI | Effect Size | 95% CI | Effect Size | 95% CI | Effect Size | |
| Frontal Lobe | 281 (18.4) | 282 (19.0) | 279 (24.6) | −10.4 to 8.5 | .000 | −13.7 to 10.1 | .001 | −10.8 to 8.7 | .001 |
| Superior frontal gyrus | 312 (16.3) | 310 (20.9) | 305 (30.5) | −16.6 to 5.3 | .012 | −18.5 to 10.4 | .004 | −8.3 to 11.1 | .002 |
| Middle frontal gyrus | 278 (23.4) | 278 (24.5) | 274 (24.9) | −13.3 to 6.8 | .005 | −15.3 to 10.0 | .002 | −10.5 to 11.7 | .000 |
| Inferior frontal gyrus | 256 (21.5) | 264 (19.5) | 258 (21.5) | −7.1 to 11.4 | .002 | −17.3 to 4.5 | .018 | −20.6 to 2.8 | .042 |
| Precentral gyrus | 301 (17.5) | 306 (21.5) | 303 (20.6) | −4.3 to 11.4 | .009 | −11.4 to 8.4 | .001 | −16.0 to 5.2 | .020 |
| Middle orbitofrontal gyrus | 288 (41.1) | 278 (46.1) | 286 (50.8) | −20.3 to 20.0 | .000 | −16.8 to 34.9 | .007 | −14.1 to 33.2 | .012 |
| Lateral orbitofrontal gyrus | 250 (29.2) | 253 (32.4) | 248 (28.8) | −14.7 to 10.3 | .001 | −21.0 to 10.1 | .007 | −20.4 to 13.3 | .003 |
| Parietal Lobe | 261 (15.9) | 269 (15.0) | 266 (20.3) | −2.9 to 13.1 | .018 | −12.6 to 7.1 | .004 | −16.8 to 0.7 | .061 |
| Postcentral gyrus | 288 (15.5) | 288 (18.9) | 289 (20.1) | −6.7 to 9.1 | .001 | −8.1 to 12.0 | .002 | −9.0 to 9.7 | .000 |
| Superior parietal gyrus | 276 (21.0) | 288 (18.3) | 283 (27.1) | −2.7 to 18.6 | .024 | −16.9 to 9.1 | .005 | −23.3 to −0.7 | .080a |
| Supramarginal gyrus | 236 (25.3) | 247 (23.8) | 241 (24.6) | −6.0 to 15.4 | .009 | −19.3 to 6.2 | .014 | −25.3 to 2.8 | .047 |
| Angular gyrus | 257 (25.1) | 270 (23.3) | 265 (24.3) | −2.5 to 18.6 | .025 | −17.1 to 7.7 | .008 | −26.8 to 0.9 | .064 |
| Precuneus | 249 (22.7) | 253 (19.4) | 252 (23.6) | −6.3 to 13.6 | .006 | −12.4 to 11.0 | .000 | −16.4 to 7.6 | .010 |
| Limbic Lobe | 273 (14.6) | 279 (15.4) | 280 (20.7) | −1.1 to 15.0 | .033 | −9.0 to 11.3 | .001 | −14.3 to 2.5 | .037 |
| Cingulate gyrus | 275 (30.8) | 282 (24.5) | 285 (28.8) | −2.8 to 22.8 | .027 | −11.4 to 17.6 | .003 | −23.4 to 9.2 | .015 |
| Hippocampus | 272 (21.9) | 276 (25.1) | 276 (27.1) | −7.0 to 14.8 | .006 | −14.7 to 13.1 | .000 | −17.6 to 8.3 | .010 |
| Occipital Lobe | 236 (15.4) | 258 (21.0) | 252 (26.4) | 7.1 to 26.7 | .117d | −18.4 to 7.8 | .009 | −32.1 to −12.5 | .287d |
| Superior occipital gyrus | 240 (29.0) | 266 (25.3) | 262 (40.5) | 6.6 to 38.1 | .083b | −23.6 to 15.3 | .002 | −42.2 to −10.7 | .179d |
| Middle occipital gyrus | 238 (17.0) | 258 (22.2) | 254 (21.7) | 7.6 to 24.8 | .138d | −15.2 to 7.3 | .007 | −31.1 to −9.8 | .221d |
| Inferior occipital gyrus | 229 (22.0) | 249 (35.0) | 241 (34.0) | −0.6 to 25.0 | .039 | −25.6 to 10.0 | .010 | −34.9 to −5.2 | .123b |
| Temporal Lobe | 244 (12.9) | 258 (18.1) | 251 (21.0) | −0.2 to 15.6 | .041 | −17.3 to 4.0 | .021 | −22.9 to −6.0 | .184d |
| Superior temporal gyrus | 226 (16.1) | 236 (12.6) | 235 (17.0) | 2.2 to 16.5 | .072a | −8.5 to 8.0 | .000 | −18.3 to −1.4 | .095a |
| Middle temporal gyrus | 270 (19.8) | 279 (14.9) | 275 (18.9) | −2.7 to 13.7 | .020 | −13.5 to 5.1 | .011 | −20.0 to 0.5 | .065 |
| Inferior temporal gyrus | 242 (16.2) | 256 (25.9) | 251 (23.4) | 1.3 to 19.1 | .056a | −16.5 to 8.4 | .006 | −25.8 to −2.8 | .107a |
| Parahippocampal gyrus | 225 (22.6) | 247 (23.4) | 237 (28.7) | 0.0 to 22.8 | .043a | −25.3 to 3.2 | .032 | −35.2 to −9.3 | .186d |
| Fusiform gyrus | 256 (29.4) | 272 (37.9) | 259 (43.1) | −14.4 to 18.8 | .001 | −35.6 to 8.2 | .021 | −34.5 to 2.5 | .055 |
a
p ≤ .05
b
p ≤ .01
c
p ≤ .005
d
p ≤ .001
1
Analyses presented for descriptive purposes only;
2
Adjusted for age