Table 1. Clinical details of the studied population.
HC (n = 275) | AHB (n = 196) | CHB-M (n = 193) | CHB-S (n = 188) | P value | |
Gender (M/F) | 156/30 | 149/47 | 153/40 | 155/33 | 0.259 |
Age (years) | 31.2±10.2 | 35.4±12.4 | 32.4±14.1 | 38.7±13.2 | <0.001 |
Total bilirubin (µmol/L) | – | 111.4±89.4 | 11.7±5.8 | 185.8±192.4 | <0.001 |
Prothrombin activity (%) | – | 95.1±24.9 | 93.5±19.7 | 81.6±20.0 | <0.001 |
Albumin (g/L) | – | 39.0±3.8 | 43.1±3.5 | 37.3±4.2 | <0.001 |
Albumin/globulin | – | 1.65±0.4 | 1.73±0.3 | 1.50±0.3 | <0.001 |
Cholinesterase (IU/L) | – | 5544.5±1746.6 | 7171.1±2324.0 | 4233.2±1548.8 | <0.001 |
ALT (IU/L) | – | 648.3±830.3 | 80.3±124.0 | 416.0±389.9 | <0.001 |
HBV DNA (logcps/mL) | – | 3.88±1.46 | 5.31±2.16 | 5.68±1.56 | <0.001 |
HBeAg negative/positive | – | 137/59 | 146/47 | 100/88 | <0.001 |
HC, healthy controls; AHB, acute hepatitis B; CHB-M, mild chronic hepatitis B; CHB-S, severe chronic hepatitis B.