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. 2013 Sep 4;8(9):e72799. doi: 10.1371/journal.pone.0072799

Table 1. Clinical details of the studied population.

HC (n = 275) AHB (n = 196) CHB-M (n = 193) CHB-S (n = 188) P value
Gender (M/F) 156/30 149/47 153/40 155/33 0.259
Age (years) 31.2±10.2 35.4±12.4 32.4±14.1 38.7±13.2 <0.001
Total bilirubin (µmol/L) 111.4±89.4 11.7±5.8 185.8±192.4 <0.001
Prothrombin activity (%) 95.1±24.9 93.5±19.7 81.6±20.0 <0.001
Albumin (g/L) 39.0±3.8 43.1±3.5 37.3±4.2 <0.001
Albumin/globulin 1.65±0.4 1.73±0.3 1.50±0.3 <0.001
Cholinesterase (IU/L) 5544.5±1746.6 7171.1±2324.0 4233.2±1548.8 <0.001
ALT (IU/L) 648.3±830.3 80.3±124.0 416.0±389.9 <0.001
HBV DNA (logcps/mL) 3.88±1.46 5.31±2.16 5.68±1.56 <0.001
HBeAg negative/positive 137/59 146/47 100/88 <0.001

HC, healthy controls; AHB, acute hepatitis B; CHB-M, mild chronic hepatitis B; CHB-S, severe chronic hepatitis B.