Table 3. G-201A frequencies and odds ratio for the association with disease progression.

Genotype	Control N (%)	Cases N (%)	OR (95% CI)	P value
HC vs. AHB
GG	237 (86.2)	161(82.2)	1.0
GA	35 (12.7)	29 (14.7)	1.22 (0.72–2.08)	0.463
AA	3 (1.1)	6 (3.1)	2.94 (0.73–11.94)	0.114
GA+AA	38 (13.8)	35(17.8)	1.36 (0.82–2.24)	0.233
**HC vs. CHB-M
GG	237 (86.2)	144 (74.7)	1.0
GA	35 (12.7)	46 (23.7)	2.16 (1.33–3.52)	0.002
AA	3 (1.1)	3 (1.6)	1.65 (0.33–8.26)	0.541
GA+AA	38 (13.8)	49 (25.3)	2.12 (1.32–3.40)	0.002
**HC vs. CHB-S
GG	237 (86.2)	138 (73.4)	1.0
GA	35 (12.7)	47 (25.0)	2.31 (1.42–3.75)	0.001
AA	3 (1.1)	3 (1.6)	1.72 (0.34–8.63)	0.342
GA+AA	38 (13.8)	50 (26.6)	2.26 (1.41–3.62)	0.001
AHB vs. CHB-M
GG	161(82.2)	144(74.7)	1.0
GA	29(14.7)	46(23.7)	1.77(1.06–2.97)	0.028
AA	6(3.1)	3(1.6)	0.56 (0.14–2.28)	0.41
GA+AA	35(17.8)	49(25.3)	1.57 (0.96–2.55)	0.071
* AHB vs. CHB-S
GG	161(82.2)	138(73.4)	1.0
GA	29(14.7)	47(25.0)	1.89 (1.13–3.17)	0.015
AA	6(3.1)	3(1.6)	0.58 (0.14–2.38)	0.48
GA+AA	35(17.8)	50(26.6)	1.67 (1.02–2.72)	0.039
CHB-M vs CHB-S
GG	144(74.7)	138(73.4)	1
GA	46(23.7)	47(25.0)	1.07 (0.67–1.70)	0.789
AA	3(1.6)	3(1.6)	1.04 (0.21–5.26)	0.959
GA+AA	49(25.3)	50(26.6)	1.07 (0.67–1.68)	0.798

^*denotes P<0.05; **denotes P<0.01.

HC, healthy controls; AHB, acute hepatitis B; CHB-M, mild chronic hepatitis B; CHB-S, severe chronic hepatitis B.