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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Addict Biol. 2013 May 27;19(1):10.1111/adb.12061. doi: 10.1111/adb.12061

Figure 1. MTEP infused into the NA core attenuates relapse after both abstinence and extinction.

Figure 1

(A) Mean number infusions attained during cocaine self-administration. (B) Intra-NA core MTEP attenuates context-induced relapse following abstinence. (C) Intra-NA core MTEP on test day has no lasting effects on extinction learning. (D) Intra-NA core MTEP significantly attenuates cue-primed reinstatement following extinction. N = 4–8/group. (E) Diagrams of the rat brain coronal sections, adapted from Paxinos and Watson (2007), show the distribution microinjection sites in the NA core. Numbers indicate distance from bregma in the anteroposterior plane. * = p<0.05 in comparison to vehicle.