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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Cortex. 2013 Feb 19;49(10):10.1016/j.cortex.2013.02.009. doi: 10.1016/j.cortex.2013.02.009

Figure 1.

Figure 1

Chromosome 11p13 deletions for subjects with WAGR syndrome. Deletion boundaries were determined using high-resolution oligonucleotide array comparative genomic hybridization (NCBI Build 36, hg 18). Deletions for each subject are shown as gray bars. Heterozygous deletions of WT1 and PAX6 are responsible for the core features of this syndrome: Wilms tumour, aniridia, and genitourinary abnormalities. Heterozygous deletion of BDNF, which is only 4Mb telomeric to PAX6, was found in approximately one-half subjects with WAGR syndrome in this study.