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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: Genet Epidemiol. 2012 May 2;36(5):438–450. doi: 10.1002/gepi.21638

Table V.

Robustness of XM to Misspecification of kf and km

Assumed kf and km Multiple of true kf and km Estimated Power (s.e.)
.053 and .010
14
.67 (.006)
.071 and .014
13
.66 (.006)
.106 and .020
12
.69 (.006)
.212 and .041 1 .72 (.006)
.423 and .082 2 .75 (.006)
.635 and .122 3 .71 (.006)
.846 and .163 4 .43 (.006)

Note. — Simulation model is II-b, with sample configuration 1. Power is assessed at significance level .0001, on the basis of 5,000 simulated replicates. kf and km are the female and male population prevalences of the trait, while kf and km are the values used in the calculation of XM. The σ^22 of equation (7) is used for the calculation of XM.