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DNA methylation levels in smokers and nonsmokers. The relative methylation levels of genes are displayed with heat maps for the 390 genes differentially methylated in smokers (A), 161 antiviral response genes represented in the methylation array (B), and 5 antiviral response genes identified as differentially methylated in smokers compared with nonsmokers (C). Methylation levels are mean standardized for each gene across all human subjects.
