Fig. 4.

Body weight change after switching to standard diet or high-protein diet. After development of diet-induced obesity on a Western-type diet or feeding of standard diet, rats were fed a standard or high-protein diet resulting in four experimental groups: standard diet/standard diet, standard diet/high-protein diet, Western-type diet/standard diet, and Western-type diet/high-protein diet. Body weight was assessed daily for a period of 14 days and expressed as daily body weight change. Data are expressed as means ± SE of 8–10 rats/group. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. standard diet/standard diet; +P < 0.05 and +++P < 0.001 vs. standard diet/high-protein diet; #P < 0.05, ##P < 0.01 and ###P < 0.001 vs. Western-type diet/standard diet.