Table 1.
Demographic and PFT information of 14 normal and 30 severely asthmatic subjects
| Normal Subjects | Severe Asthmatics | P (From t-Test) | |
|---|---|---|---|
| Age, yr | 34.5 ± 3.9 | 47.2 ± 2.2 | <0.01 |
| BMI | 25.6 ± 1.5 | 31.1 ± 1.3 | <0.05 |
| Asthma duration | 28.2 ± 3.3 | ||
| Sex, No. (%Female) | 10 (71%) | 18 (60%) | |
| Race, No. (White nonhispanic/African American/Other) | 10/1/3 (71%/7%/21%) | 25/3/2 (83%/10%/7%) | |
| TLC, % predicted | 96 ± 3 | 97 ± 3 | 0.75 |
| FRC, % predicted | 90 ± 5 | 102 ± 5 | 0.12 |
| RV, % predicted | 90 ± 6 | 134 ± 9 | <0.0005 |
| FVC, % predicted | 98 ± 2 | 71 ± 3 | <1.0 × 10−7 |
| FEV1, % predicted | 96 ± 3 | 55 ± 4 | <1.0 × 10−10 |
| FEV1/FVC × 100 | 81 ± 1 | 60 ± 2 | <5.0 × 10−10 |
| RV/TLC × 100 | 27 ± 2 | 44 ± 2 | <5.0 × 10−6 |
Values are means ± SE. PFT, pulmonary function test; TLC, total lung capacity; FRC, functional residual capacity; RV, residual volume; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s. TLC, FRC, and RV of 1 normal subject and 1 severely asthmatic subject were not available.