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. 2011 Jul;34(2):213–220. doi: 10.1111/j.1460-9568.2011.07763.x

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© 2011 The Authors. European Journal of Neuroscience © 2011 Federation of European Neuroscience Societies and Blackwell Publishing Ltd

This is an open access article under the terms of the Creative Commons License, which permits use and distribution in any medium, provided the original work is properly cited.

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FIG. 2 — (A) Typical sEPSCs from wild-type (left) and P2X4^−/− (right) mice. Inset: average event (n = 200) at higher time resolution. (B) EPSC amplitude histograms do not differ between wild-type (black) and knockout (gray) mice. Inset: cumulative probability plot. (C) CNQX (30 μm) blocks all sEPSCs. (D) Normalized average amplitude of sEPSCs of wild-type (open circles, n = 4) and P2X4^−/− (triangles, n = 5) mice during 30 min recording. (E) Tetanic stimulation (arrow) does not produce long-lasting potentiation of the amplitudes of sEPSCs in wild-type (open circles, n = 5) or P2X4^−/− (open triangles, n = 4) mice. Holding potentials, −60 mV.