Table 1. Comparison of clinicopathological characteristics (unilateral versus first tumor of BiBC).
| Characteristics | Unilateral (n = 1650) | First tumor of BiBC (n = 48) | P value |
|---|---|---|---|
| Median age (years) (range) | 48 (21 ~ 89) | 47.5 (27 ~ 69) | 0.266 |
| Nodal status | |||
| N0 | 678 (41.1%) | 12 (25.0%) | 0.000 |
| N1 | 477 (28.9%) | 12 (25.0%) | |
| N2 | 379 (23.0%) | 11 (22.9%) | |
| N3 | 116 (7.0%) | 13 (27.1%) | |
| TNM stage | |||
| I | 107 (6.5%) | 3 (6.3%) | 0.082 |
| II | 757 (45.9%) | 14 (29.2%) | |
| III | 786 (47.6%) | 31 (64.5%) | |
| Histologic type | |||
| Infiltrating Duct Carcinoma | 1089 (66.0%) | 35 (73.0%) | 0.003 |
| Infiltrating Lobular Carcinoma | 78 (4.7%) | 5 (10.4%) | |
| Others | 483 (29.3%) | 8 (16.7%) | |
| ER status | |||
| Positive | 1077 (65.3%) | 28 (58.6%) | 0.457 |
| Negative | 573 (34.7%) | 20 (41.4%) | |
| PR status | |||
| Positive | 945 (57.3%) | 25 (52.0%) | 0.548 |
| Negative | 705 (42.7%) | 23 (47.9%) | |
| HER-2 status | |||
| Positive | 470 (28.5%) | 15 (31.3%) | 0.818 |
| Negative | 1180 (71.5%) | 33 (68.8%) | |
| Family history of breast cancer | |||
| Positive | 104 (6.3%) | 7 (14.6%) | 0.022 |
| Negative | 1546 (93.7%) | 41 (85.4%) | |
| Bone metastasis | |||
| Positive | 181 (11.0%) | 11 (22.9%) | 0.011 |
| Negative | 1469 (89.0%) | 37 (77.1%) | |
| Visceral metastasis | |||
| Positive | 219 (13.3%) | 17 (35.4%) | 0.000 |
| Negative | 1431 (86.7%) | 31 (64.6%) |