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. 2013 Aug 16;3(8):e133. doi: 10.1038/bcj.2013.31

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Copyright © 2013 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Linear correlation was shown between the percentage of LAIPs+ blasts and different titers of dilution from five B-ALL samples with different LAIPs features. The LAIP combinations of samples from numbers 1 to 5 were shown as: CD10-CD34+/58st/38dim, CD10-CD34+, CD10+CD34+CD33+/CD38dim/45dim, CD10+CD34+CD45dim/CD19st/CD66c+ and CD10+CD34+58st/38dim/CD13+. ‘Undiluted' and ‘Normal' on the X-axis mean the original B-ALL BM sample and regenerating BM sample, respectively. The minimum MRD quantity by eight-color flow cytometric assay according to samples from numbers 1 to 5 were 0.0007, 0.0015, 0.0005, 0.0005 and 0.0008%, respectively. The data were not shown on the Figure when the number of LAIP+ blasts were <10 within 2 × 10⁶ WBCs (<0.0005%).