Table 1. TRAM-34 concentration in mouse brains.

Time (h)	TRAM-34 (nM)
0	0
2	1367±201
12	424±39

SCID mice (n=3 for each time point) were injected with GL-15 cells as described in the text and treated for 5 weeks with TRAM-34. At different time points after the last treatment, mice were sacrificed, the brains were isolated, and analyzed using HPLC/MS as described in the text.