Skip to main content
. Author manuscript; available in PMC: 2013 Sep 5.
Published in final edited form as: Cancer Res. 2010 Apr 27;70(10):3890–3895. doi: 10.1158/0008-5472.CAN-10-0155

Figure 3.

Figure 3

DP and DL enhances the in vivo anti-tumor efficacy of G47Δ. (a) Assessment of Du145 tumor growth. * P < 0.05 for Mock (n=7) or G47Δ only (n=7) versus G47Δ + DP (n=6) or + DL (n=6) at d28; ** P < 0.05 for G47Δ only versus G47Δ in combination with either DP or DL at d32 and d36; *** P < 0.05 for Mock versus G47Δ only; G47Δ versus G47Δ in combination with either DP or DL at d45. † P < 0.01 for Mock versus G47Δ in combination with either DP or DL at d32, d36 and d45. (b) Du145 tumor weights were assessed for the indicated treatment groups 45 days post-implantation. P values are indicated. (c) Evaluation of DP and DL augmented G47Δ replication in prostate cancer surgical specimens. Each color dot indicates a different prostate surgical specimen (n=5).