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. 2013 Jun 19;41(16):7804–7814. doi: 10.1093/nar/gkt487

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Interface disruption mechanism as determined from the SMD force-extension profiles for (A) yeast PCNA and (B) E. coli β-clamp. The force-extension profile is smoothed by adjacent averaging for a 100-frame window. Representative snapshots of the subunit interfaces at different stages of separation are shown. Arrows indicate the correspondence to distinct peaks in the force-extension profiles.