Table 1.
Representative RNA aptamers assayed for their ex vivo inhibition of HCV replication.
| Group | Aptamer | Sequence * |
|---|---|---|
| I (5'-RGUGRR-3' |
P8-27 |
|
| P9-39 |
|
|
| I y IV | P6-45 |
|
| II 5'-GGYUGUG-3' |
P7-54 |
|
| P9-34 |
|
|
| II y IV | P6-91 |
|
| III 5'-YGGGYR-3' |
P7-14 |
|
| P8-65 |
|
|
| P8-68 |
|
|
| P8-71 |
|
|
| III y IV | P6-99 |
|
| P9-15 |
|
|
| IV 5'-YGUGUG-3' |
P6-2 |
|
| P6-20 |
|
|
| P9-37 |
|
|
| V 5'-UGGGGR-3' |
P9-8 |
|
* Sequence of the variable region is shown. Common sequence is highlighted in grey for group I aptamers, in blue for group II aptamers, boxed for group III aptamers, highlighted in green for group IV aptamers and in red for group V aptamers.