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Synthesis of 5-amino (or hydroxy)-4-carbomethoxy-2-methylbenzothienopyridines.
| Entry | Azide (%yield) | Phosphorane (%yield) | Benzothienopyridine (%yield) |
|---|---|---|---|
| 1 | 20a (77%) | 21a (84%) | 23a (91%) |
| 2 | 20b (80%) | 21b (40%) | 23b (14%) |
| 3 | 20c (30%) | 21c (no product) | 23c (no product) |
| 4 | 20a (77%) | 22a (33%) | 24a (40%) |
| 5 | 20b (80%) | 22b (20%) | 24b (no product) |
| 6 | 20c (30%) | 22c (no product) | 24c (no product) |
