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Synthesis of 4-carbomethoxy-6-hydroxy-(or amine)-2-methylbenzothienopyridines.
| Entry | Azide (%yield) | Phosphorane (%yield) | Benzothienopyridine (%yield) |
|---|---|---|---|
| 1 | 26a (55%) | 27a (58%) | 29a (35%) |
| 2 | 26b (28%) | 27b (79%) | 29b (13%) |
| 3 | 26c (62%) | 27c (49%) | 29c (no product) |
| 4 | 26a (55%) | 28a (74%) | 30a (52%) |
| 5 | 26b (28%) | 28b (81%) | 30b (58%) |
| 6 | 26c (62%) | 28c (no product) | 30c (no product) |
