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(a) Effect of MFG-E8 on the luminescence profile (retinal luminescence)/(RPE luminescence), following co-subretinal injection with AAV-luciferase in adult mice (n = 9), p = 0.03. Overall the ratio of retina to RPE transduction is reduced when MFG-E8 is present in the viral adjuvant. The retinal luminescence (b) shows the absolute reduction in retinal transduction due to MFG-E8, p = 0.04.
