Table 4.
Combined association of passive smoking exposure and CYP1A1MspI and CYP1A1HincII genotypes with dysmenorrheaǂ
Passive
Smoking |
MspI | HincII | Dysmenorrhea
|
|||
---|---|---|---|---|---|---|
N(%) | OR* | 95%CI | P | |||
No† | T/T6235 | Ile/Val462 or Val/Val462 | 11(21.6) | 1.0 | --- | --- |
No | T/T6235 | Ile/Ile462 | 11(28.9) | 1.5 | 0.6~3.9 | 0.426 |
No | T/C6235 | Ile/Val462 or Val/Val462 | 69(30.8) | 1.6 | 0.8~3.3 | 0.193 |
No | T/C6235 | Ile/Ile462 | 51(24.6) | 1.2 | 0.6~2.5 | 0.646 |
No | C/C6235 | Ile/Val462 or Val/Val462 | 20(38.5) | 2.3 | 1.0~5.4 | 0.064 |
No | C/C6235 | Ile/Ile462 | 79(28.2) | 1.4 | 0.7~2.9 | 0.328 |
Yes | T/T6235 | Ile/Val462 or Val/Val462 | 10(19.6) | 0.9 | 0.3~2.3 | 0.807 |
Yes | T/T6235 | Ile/Ile462 | 9(39.1) | 2.3 | 0.8~6.8 | 0.120 |
Yes | T/C6235 | Ile/Val462 or Val/Val462 | 71(34.6) | 1.9 | 0.9~4.0 | 0.077 |
Yes | T/C6235 | Ile/Ile462 | 66(32.8) | 1.8 | 0.9~3.7 | 0.122 |
Yes | C/C6235 | Ile/Val462 or Val/Val462 | 17(31.5) | 1.7 | 0.7~4.0 | 0.253 |
Yes | C/C6235 | Ile/Ile462 | 107(41.3) | 2.6 | 1.3~5.2 | 0.010 |
Estimates were derived from logistic regression models with adjustment for perceived stress.
Reference category.
T/T6235 indicates homozygous wild type; T/C6235 indicates heterozygous variant type; C/C6235 indicates homozygous variant type; Ile/Ile462 indicates homozygous wild type, Ile/ Val462 indicates heterozygous variant type, and Val/Val 462 indicates homozygous variant type.