Figure 8.

Pancreatic T5 mRNA expression in B6J and B6N substrains. A: Pancreatic T5 expression in saline-injected control mice and in repetitive cerulein-injected mice after induction of CP. T5 expression was significantly induced after induction of CP in both B6N and B6J substrains. B: Pancreatic T5 expression in mice after acute cerulein-induced injury. Similar to the increase in CP, T5 mRNA expression was significantly induced in both substrains after acute injury. T5 mRNA expression was normalized to Rplp0 and expressed as fold increase over the level in B6N saline-treated control mice. Data are expressed as means with 95% confidence intervals. Confidence intervals were calculated using the ΔC_T values before exponential transformation to fold increase in mRNA and are therefore asymmetric about the means. n = 6. ^∗P < 0.05.