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. 2013 Sep;183(3):692–708. doi: 10.1016/j.ajpath.2013.05.020

Figure 9.

Figure 9

Pancreatic Ccl8 expression in B6J and B6N substrains. A: Ccl8 expression in the pancreas after induction of CP. Ccl8 was strongly up-regulated in the pancreas of mice with CP, compared with control mice. The up-regulation in B6J mice was not significantly greater than in B6N mice (P = 0.02). B: Ccl8 expression in the pancreas after acute cerulein-induced injury. Acute injury induced Ccl8 mRNA increase approximately 2.5-fold in B6J mice, but not in B6N mice. Ccl8 mRNA expression was normalized to Rplp0 and expressed as fold increase over the level in B6N saline-treated control mice. Data are expressed as means with 95% confidence intervals. Confidence intervals were calculated using the ΔCT values before exponential transformation to fold increase in mRNA and are therefore asymmetric about the means. n = 6. P < 0.05.