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. 2013 Sep;183(3):951–963. doi: 10.1016/j.ajpath.2013.05.021

Figure 2.

Figure 2

NKX3.1 binds to the RAMP1 gene in human and mouse prostate cells. Integrated Genome Browser screenshots of NKX3.1 binding sites in the mouse (A) and human (LNCaP) (B) genomes. Binding of NKX3.1 is indicated by arrows. IgG and Nkx3.1 knockout tissue served as a negative control. C: ChIP-qPCR confirmation of the three NKX3.1 binding sites in the RAMP1 gene in LNCaP cells. An androgen receptor (AR) promoter region known to bind NKX3.1 was used as a positive control, whereas IgG served as a negative control.