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Signaling pathway mediation of IP-10 and I-TAC expression. A: IP-10 and B: I-TAC secretion by decidual cells treated with vehicle, TNF-α, IFN-γ, and TNF-α + IFN-γ with or without NFκB inhibitor BAY, or JAT/STAT inhibitor (MTA) or BAY + MTA (n = 3, mean ± SEM). *P < 0.05, **P < 0.01, and ***P < 0.005. (C) Representative binding of decidual cell–derived nuclear NFκB subunits p65 and p50 to NFκB-RE by E-EMSA (n = 2).
