Figure 8.

CD163⁺, procollagen⁺, and osteocalcin⁺ cells accumulate in other tissues of NSF patients. A: Paucity of CD163⁺ cells (brown) in the coronary artery of an end-stage renal disease patient without NSF. B: Significant CD163⁺ cells (brown) are present in the coronary artery of this patient who died with NSF. C: The presence of CD163 (brown) and procollagen-1 (red) double-positive cells in the aortic media and adventitia of a patient who died with NSF.The aorta showed significant intimal and medial calcification. D: Myocardium of a patient who died with NSF shows increased CD163⁺ cells (brown). E: A high-power view confirming increased CD163⁺ cells (brown) in the myocardium of a patient with NSF. F: A lining of a vessel (V) in the periaortic adventitia of a NSF patient lined by CD163 (brown) and procollagen-1 (red) double-positive cells. Note red blood cells in the lumen of the vessel shown. Small numbers of scattered CD163⁺ cells (brown) in the myocardium of patients with end-stage renal disease (G) and end-stage renal disease patients with head and neck cancer (H). Original magnification: ×40 (A, B, D, G, and H); ×200 (C and E); ×600 (F).