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. 2012 Jun 30;55(2):29–40.

Table 6.  Association of FTO genotype with MS.

Method Subject Definition of MS SNP Association
Present study Cohort study Japanese Japanese definition rs9939609
(Izumo region, Shimane) rs1121980
rs1558902 +
NCEP-ATPIII rs9939609 +
rs1121980 +
rs1558902 +
Shimaoka et al., 2010 Cross-sectional study Japanese Japanese definition rs9939609
(Tanno-Sobetsu, Hokkaido) rs1121980
rs1558902
Tabara et al., 2009 Case-control study Japanese NCEP-ATPIII rs9939609
(Ehime)
Sjögren et al., 2008 Cohort study Swedish Ordinal rs9939609 +
(reference to NCEP-ATPIII, IDF)
Al-Attar et al., 2008 Meta-analysis South Asian IDF rs9939609 +
Chinese
Oji-Cree
Greenland Inuit
South Asian NCEP-ATPIII rs9939609
Chinese
Oji-Cree
Greenland Inuit +

FTO, fat mass and obesity associated gene; IDF, International Diabetes Federation; MS, metabolic syndrome; NCEP-ATPIII, National Cholesterol Education Program-Adult Treatment panel III; SNP, single nucleotide polymorphism.