Immunosuppressive effects of B7-H4+ monocytes on CD4+ T
cells.
a: B7-H4+ monocytes suppress the proliferation of
CD4+ T cells compared with B7-H4– monocytes, as evaluated by
CFSE assays.
b: B7-H4+ monocytes significantly suppress IFN-gamma
secretion by CD4+ T cells compared with B7-H4– monocytes
(P = 0.023).
CFSE, carboxyfluorescein succinimidyl ester.