Figure 4. .

Effect of DFP on NaIO₃-induced changes in gene expression within the RPE shown by qPCR. DFP treatment caused no changes in Tfr mRNA levels relative to the control group (DFP and NaIO₃ untreated) and the NaIO₃ only–treated group (A). Rpe65 mRNA levels were significantly higher in the DFP-treated group (B). DFP treatment significantly decreased Hmox1 and C3 mRNA (C, D) following NaIO₃ tail veil injection. ANOVA with a Tukey post test was used to compare the means between the groups. The asterisk denotes significant difference (P < 0.05) between the means of the groups.