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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Prostate Cancer Prostatic Dis. 2013 Jul 9;16(3):277–284. doi: 10.1038/pcan.2013.18

Figure 1. Lower Arylsulfatase B H-scores predict recurrence in paired prostate cancer cases.

Figure 1

A. Mean ARSB H-scores were calculated for stroma, epithelium, and combined stroma and epithelium for 22 pairs of prostate cancer cases that differed by recurrence vs. non-recurrence at 4 or more years of followup. Recurrences had lower mean ARSB H-scores for stroma (0.10 ± 0.08 vs. 0.19 ± 0.09), epithelium (0.48 ± 0.32 vs. 0.86 ± 0.24) and combined stroma and epithelium (0.28 ± 0.26 vs. 0.62 ± 0.28) and differences were highly significant (p=0.0021, p=0.0003, p=0.0006, respectively, paired t-test, two-tailed).

B. Scattergram shows the ARSB H-scores in the 22 pairs of prostate cancer cases for epithelium and stroma combined. H-scores less than 0.25 accurately predicted recurrence, and H-scores over 0.70 were associated with non-recurrence in 8 of 9 cases. Green squares indicate non-recurrence, and red diamonds indicate recurrence.