Table 1.
Clinical, experimental and demographic data for the attention-deficit/hyperactivity disorder combined type (ADHD-CT) and control participants.
| ADHD-CT (DAT110/6) |
Control (DAT110/6) |
|||||
|---|---|---|---|---|---|---|
| Mean (SD) | 2 copies (n=15) | <2 copies (n=14) | 2 copies (n=16) | <2 copies (n=14) | Significance Test | p |
| Age (years) | 15.60 (2.35) |
15.35 (2.06) |
15.35 (1.4) |
15.87 (2.06) |
Fgroup(1, 55)=0.06 Fhaplotype(1, 55)=0.07 Finteraction (1, 55)=0.54 |
.80 .79 .47 |
| IQ | 109.4 (12.8) |
101.07 (12.97) |
111.06 (9.9) |
115.5 (12.20) |
Fgroup(1, 55)=6.63 Fhaplotype(1, 55)=0.39 Finteraction (1, 55)=4.18 |
.013 .54 .046 |
| Conners' DSM-IV ADHD Inattention ratings (parent) |
65.67 (10.77) |
72.5 (8.23) |
46.53 (4.61) |
47.29 (6.35) |
Fgroup(1, 54)=115.56 Fhaplotype(1, 54)=3.38 Finteraction (1, 54)=2.17 |
<.001 .071 .15 |
| Conners' DSM-IV ADHD Hyperactivity/Impulsivity ratings (parent) |
77 (13.94) |
81.07 (12.80) |
47.4 (7.19) |
48.14 (6.13) |
Fgroup(1, 54)=126.14 Fhaplotype(1, 54)=0.75 Finteraction (1, 54)=0.36 |
<.001 .39 .55 |
| Conners' DSM-IV ADHD Total ratings (parent) |
72.6 (12.87) |
79.29 (9.98) |
46.53 (5.42) |
47.36 (6.03) |
Fgroup(1, 54)=146.16 Fhaplotype(1, 54)=2.45 Finteraction (1, 54)=1.49 |
<.001 .12 .23 |
| Mean response time, Gain trials (SE) | 609.24 (19.72) |
631.47 (20.42) |
595.01 (19.10) |
571.31 (20.42) |
Fgroup(1, 55)=3.49 Fhaplotype(1, 55)=0.00 Finteraction (1, 55)=1.33 |
.067 .97 .25 |
| Mean response time, Loss-avoidance trials (SE) | 621.31 (19.29) |
638.49 (19.97) |
604.33 (18.68) |
580.01 (19.97) |
Fgroup(1, 55)=3.75 Fhaplotype(1, 55)=0.03 Finteraction (1, 55)=1.13 |
.058 .86 .29 |
| Subjective ratings of excitement induced by gain-anticipation (£5 vs. £0) | 41.73 (17.06) |
39.54 (25.08) |
45.13 (22.76) |
49.57 (13.38) |
Fgroup(1, 54)=1.50 Fhaplotype(1, 54)=0.04 Finteraction (1, 54)=0.37 |
.23 .84 .55 |
| Subjective ratings of effort invested in large incentive trials (£5 vs. £0) | 40.47 (23.46) |
33.46 (29.28) |
42.20 (23.85) |
30.14 (17.51) |
Fgroup(1, 54)=0.01 Fhaplotype(1, 54)=2.12 Finteraction (1, 54)=0.15 |
.90 .15 .70 |
| Success rate (%) | 78.29 (0.48) |
77.59 (0.50) |
78.48 (0.47) |
78.48 (0.50) |
Fgroup(1, 55)=1.22 Fhaplotype(1, 55)=0.51 Finteraction (1, 55)=0.53 |
.27 .48 .47 |
| Total Earned (£) | 140 (3.14) |
140.93 (3.25) |
141.44 (3.04) |
135 (3.25) |
Fgroup(1, 54)=0.50 Fhaplotype(1, 54)=0.75 Finteraction (1, 54)=1.35 |
.48 .39 .25 |
Note: DAT1 = dopamine transporter gene; IQ = intelligence quotient; SE = standard error.