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. 2013 Sep 5;9(9):e1003214. doi: 10.1371/journal.pcbi.1003214

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© 2013 Mathelier, Wasserman

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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TFFMs allowing a flexible length motif have been compared to PWMs, DWMs, GLAM2, and fixed-length TFFMs on STAT4 (A) and STAT6 (B) ChIP-seq data. Flexible TFFMs do not significantly perform better than fixed-length TFFMs. DWMs, PWMs, and GLAM2 produce a lower discriminative power than the TFFMs.