Table 2. Pearson correlation coefficients between experimentally measured and predicted changes in affinity correlations.

Isoform	Method	Pearson correlation coefficient
isoA	PWM	0.65
	DWM	0.66
	0-order TFFM	0.76
	1st-order TFFM	0.74
	detailed TFFM	0.75
isoB	PWM	0.60
	DWM	0.61
	0-order TFFM	0.77
	1st-order TFFM	0.75
	detailed TFFM	0.75

The table contains the Pearson correlation coefficients computed between the experimentally measured and predicted changes in DNA-binding affinity between the optimal sequence and mutated ones. Correlations have been computed for both Max TF isoforms and all the predictive methods. Associated -value have been computed for each Pearson correlation coefficient value and are .