Table 1. Motor profile of the pre-symptomatic and symptomatic SOD1(G93A) mice.
| 4-6 weeks old |
12-15 weeks old |
|||
|---|---|---|---|---|
| WT | SOD1(G93A) | WT | SOD1(G93A) | |
| n (mice) | 16 (9M, 7F) | 11 (5M, 6F) | 10 (4M, 6F) | 10 (6M, 4F) |
| Body weight (g) | 19 ± 0.72 | 18 ± 0.95 | 24 ± 0.93 | 24 ± 0.89 |
| LF at 5 rpm (s) | 242 ± 13.4 | 262 ± 14.0 | 267 ± 12.3 | 246 ± 23.6 |
| LF at10rpm (s) | 257 ± 11.8 | 236 ± 21.8 | 263 ± 13.9 | 181 ± 31.3# |
The values are mean±SEM. Results obtained from aged-matched SOD1(G93A) and WT mice were compared (#p<0.05, Mann-Whitney test). LF, latency-to-fall; rpm, rotations-per-minute