Table 2. Colon tumor parameters of saline- and AOM-injected rats fed diets with or without acrylamide for 24 weeks.^a .

		Control		Acrylamide
				0.5 mg/kg	1.0 mg/kg		2.0 mg/kg
Saline-injected rats
Total rats		8		8	8		8
Tumor-bearing rats		0		0	0		0
Tumor incidenceb		0		0	0		0
AOM-injected rats
Total rats		24		24	24		24
Tumor-bearing rats		13		14	12		16
Tumor incidenceb		54.17		58.33	50.00		66.67
Total Tumors		22		19	16		25
Tumor multiplicityc		1.69 ± 0.32		1.36 ± 0.18	1.33 ± 0.14		1.56 ± 0.24
Tumor sizec (mm2)		10.68 ± 1.85		6.91 ± 1.16	13.68 ± 4.04		25.18± 8.34*
Tumor burdenc,d (mm2)		19.27 ± 3.92		8.75 ± 2.74	17.93 ± 3.11		35.52 ± 9.96*

^a All values recorded at the time of necropsy, 20 weeks post saline/AOM injections; ^b % rats with tumors; ^c mean ± SE; ^d total area occupied by tumors in each tumor-bearing rat in the group per total number of tumor-bearing rats in the group; and ^* statistical different from control (0 mg/kg acrylamide/diet) at p < 0.05.