Table 3.
Associations between maternal exposure to persistent organochlorines (per IQR increase) and offspring body size in the CPP, 1959–1965.
| Chemicals (μg/L) | IQR | Overweighta | Obese | BMI (kg/m2) |
|---|---|---|---|---|
| ORb (95% CI) | ORb (95% CI) | βb,c (95% CI) | ||
| β-HCH | 1.11 | 1.00 (0.87, 1.16) | 1.03 (0.84, 1.24) | 0.01 (–0.06, 0.09) |
| p,p’-DDE | 19.42 | 0.88 (0.72, 1.07) | 1.00 (0.75, 1.32) | –0.03 (–0.18, 0.11) |
| p,p’-DDT | 7.70 | 0.97 (0.79, 1.19) | 1.16 (0.88, 1.54) | 0.02 (–0.12, 0.16) |
| Dieldrin | 0.49 | 1.00 (0.83, 1.22) | 1.32 (1.01, 1.73) | 0.09 (–0.12, 0.29) |
| Heptachlor epoxide | 0.50 | 1.06 (0.82, 1.36) | 0.96 (0.48, 1.93) | 0.00 (–0.18, 0.18) |
| HCB | 0.23 | 1.00 (0.98, 1.03) | 1.02 (0.99, 1.05) | 0.02 (–0.02, 0.07) |
| trans-Nonachlor | 0.32 | 1.05 (0.82, 1.34) | 1.00 (0.67, 1.51) | 0.01 (–0.15, 0.17) |
| Oxychlordane | 0.37 | 0.92 (0.67, 1.26) | 1.00 (0.53, 1.90) | –0.01 (–0.20, 0.17) |
| Total PCBs | 1.99 | 0.97 (0.80, 1.18) | 1.01 (0.71, 1.44) | 0.01 (–0.12, 0.14) |
| aIncludes overweight and obese. bAdjusted for total cholesterol, triglycerides, study center, mother’s race, socioeconomic index, education, smoking during pregnancy, prepregnancy BMI, and child’s sex and birth order. cAdditionally adjusted for child’s exact age at anthropometric measurements. | ||||