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. 2013 Sep 5;8(9):e74439. doi: 10.1371/journal.pone.0074439

Table 3. Function of differentially-expressed identified proteins.

Spot no. a Proteinb Geneb GO accessionc Biological process / Functionc
1 α-Enolase ENO1 0006096; 0030308 Glycolysis; Negative regulation of cell growth
2 ATP synthase subunit β ATP5B 0022904; 0005753 Respiratory electron transport chain; Mitochondrial H+-transporting ATP synthase complex
3, 115 S-Arrestin SAG 0009586; 0007601 Rhodopsin mediated phototransduction; Visual perception
5 β-Crystallin B2 CRYBB2 0005212; 0007601 Structural constituent of eye lens; Visual perception
7 HSC70 HSPA8 0061077; 0006950 Chaperone-mediated protein folding; Response to stress
12 Stathmin STMN1 0007019; 0033556; 0030154 Microtubule depolymerization; Intracellular signat transduction; Cell differentiation
13, 18 DDAH1 DDAH1 0016403; 0045429; 0017014 Dimethylargininase activity; Positive regulation of NO biosynthetic process; Protein nitrosylation
20, 237 γ-Enolase ENO2 0006096; 0001917 Glycolysis; Photoreceptor inner segment
21 GRP78 HSPA5 0030968; 0051087; 0043066 ER unfolded protein response; Chaperone binding; Negative regulation of apoptotic process
31 GAPDH GAPDH 0006096; 0051402; 0000226 Glycolysis; Neuron apoptotic process; Microtubule cytoskeleton organization
33 PPA1 PPA1 0004427 Inorganic diphosphatase activity
34 Calbindin CALB1 0005509; 0048167; 0010842 Calcium ion binding; Regulation of synaptic plasticity; Retina layer formation
37 NDPK B NME2 0004550; 0043066; 0010976 Nucleoside diphosphate kinase activity; Negative regulation of apoptotic process; Positive regulation of neuron projection development
42 COX subunit 5A COX5A 0022904 Respiratory electron transport chain
91 γ-Synuclein SNCG 0014059; 0005815 Regulation of dopamine secretion; Microtubule organizing centre
a

Refers to that indicated in Figure 1C.

b

The protein pertaining to each spot and the name of its encoding gene are indicated.

c

Accession number(s) for each protein and most relevant associations found in the GO database in relation with the scope of this article.