Table 3. Function of differentially-expressed identified proteins.
Spot no. a | Proteinb | Geneb | GO accessionc | Biological process / Functionc |
---|---|---|---|---|
1 | α-Enolase | ENO1 | 0006096; 0030308 | Glycolysis; Negative regulation of cell growth |
2 | ATP synthase subunit β | ATP5B | 0022904; 0005753 | Respiratory electron transport chain; Mitochondrial H+-transporting ATP synthase complex |
3, 115 | S-Arrestin | SAG | 0009586; 0007601 | Rhodopsin mediated phototransduction; Visual perception |
5 | β-Crystallin B2 | CRYBB2 | 0005212; 0007601 | Structural constituent of eye lens; Visual perception |
7 | HSC70 | HSPA8 | 0061077; 0006950 | Chaperone-mediated protein folding; Response to stress |
12 | Stathmin | STMN1 | 0007019; 0033556; 0030154 | Microtubule depolymerization; Intracellular signat transduction; Cell differentiation |
13, 18 | DDAH1 | DDAH1 | 0016403; 0045429; 0017014 | Dimethylargininase activity; Positive regulation of NO biosynthetic process; Protein nitrosylation |
20, 237 | γ-Enolase | ENO2 | 0006096; 0001917 | Glycolysis; Photoreceptor inner segment |
21 | GRP78 | HSPA5 | 0030968; 0051087; 0043066 | ER unfolded protein response; Chaperone binding; Negative regulation of apoptotic process |
31 | GAPDH | GAPDH | 0006096; 0051402; 0000226 | Glycolysis; Neuron apoptotic process; Microtubule cytoskeleton organization |
33 | PPA1 | PPA1 | 0004427 | Inorganic diphosphatase activity |
34 | Calbindin | CALB1 | 0005509; 0048167; 0010842 | Calcium ion binding; Regulation of synaptic plasticity; Retina layer formation |
37 | NDPK B | NME2 | 0004550; 0043066; 0010976 | Nucleoside diphosphate kinase activity; Negative regulation of apoptotic process; Positive regulation of neuron projection development |
42 | COX subunit 5A | COX5A | 0022904 | Respiratory electron transport chain |
91 | γ-Synuclein | SNCG | 0014059; 0005815 | Regulation of dopamine secretion; Microtubule organizing centre |
Refers to that indicated in Figure 1C.
The protein pertaining to each spot and the name of its encoding gene are indicated.
Accession number(s) for each protein and most relevant associations found in the GO database in relation with the scope of this article.