Table 3. Raw (%) and adjusted (OR) rates of pregnancy salvage following combined anti-coagulant therapy with aspirin and LMWH treatment.
Factors | N | % of pregnancy salvage (n) | OR (95%CI) | p-value | |
Total Cohort | 187 | ||||
PCOS | No | 91 | 60.43 (55) | 1 | |
Yes | 96 | 72.91 (70) | 0.78 (0.63–1.57) | 0.33 | |
HHcy | No (≤12 µmol/L) | 111 | 54.95 (61) | 1 | |
Yes (≥12 µmol/L) | 76 | 84.21 (64) | 1.55 (1.29–1.88) | 0.0001 | |
IR | No (HOMA2-IR≤2.1) | 123 | 60.16 (74) | 1 | |
Yes (HOMA2-IR≥2.1) | 64 | 79.68 (51) | 1.20 (0.82–1.43) | 0.02 | |
Obesity | No (BMI≤30 kg/m2) | 134 | 73.88 (99) | 1 | |
Yes (BMI≥30 kg/m2) | 53 | 49.05 (26) | 0.91 (0.53–1.56) | 0.72 |
HHcy: hyperhomocysteinemia (Hcy>12 µmol/l); IR: insulin resistance (HOMA2-IR>2.1); obesity: BMI ≥30 kg/m2; OR: odds ratio; CI: confidence interval.
Column percentages presented for univariate analysis.