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. 2013 Sep 5;8(9):e71935. doi: 10.1371/journal.pone.0071935

Figure 6. Assay demonstrating cytochrome c release in HeLa cells.

Figure 6

Flow cytometry was used to show the effects of these compounds on cytochrome c release from the mitochondria into the cytoplasm in HeLa cells. Vehicle-treated control cells (A), 2-methoxyestradiol-bis-sulphamate-treated cells (B), ESE-16-treated cells (C), ESE-15-one-treated cells (D) and EMBS-treated cells (E) following 24 h of exposure. Cytochrome c release was evident in all three compound-treated cells when compared to the vehicle-treated cells.