Figure 4. Sequence alignment and annotated tertiary motifs in SAM-III riboswitches.
(A) Sequence alignment of SAM-III riboswitches where gray shaded columns indicate the highly conserved nucleotide positions. For clarity, not all tertiary motif positions are numbered. Base-triple positions that are not conserved are in cyan shaded columns. (B) Tertiary structure of the E. faecalis SAM-III riboswitch [21] (PDB ID = 3e5c). The ligand is represented as spheres and the highly conserved nucleotides are in wire representation. Magnification of the triples using numbering for 3e5e are presented in red (A73-G90-C25) and blue (A27-G66-G71).
