Skip to main content
. 2013 Sep 5;9(9):e1003752. doi: 10.1371/journal.pgen.1003752

Figure 6. NDN expression in PWS patients.

Figure 6

Detection of NDN transcripts revealed by ISH, and using a NDN anti-sense probe, on PVN brain sections from control individuals (A,C,E) and PWS patients (B,D,F). A NDN-sense probe was used as a negative control. IHC on SON brain sections, using a NECDIN specific antibody, was performed on the same control and PWS patients. The expression was studied in the 94-118 adult control male (A) and the 95104 adult PWS patient with a maternal uniparental disomy (B), in the 88-017 adult control male (C) and the 00-028 PWS adult patient with a deletion (D), in the 97-153 control infant (E) and the 99-079 PWS infant with a deletion (F). Scale bar: 20 µm.