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. 2013 Sep 5;9(9):e1003769. doi: 10.1371/journal.pgen.1003769

Figure 7. Uve1 is required for efficient repair of mitochondrial DNA damage post UV stress.

Figure 7

Two independent experiments were carried out on different days. (A, C) Agarose gels for the PCR amplification of mitochondrial and nuclear DNA on template DNA from undamaged control cells and template DNA from cells exposed to UV stress 50 J/m2. C. neoformans var. grubii strains KN99α (WT) and AI191 (uve1Δ) PCR amplification pattern for no stress, 0 hour, 1 hour, 4 hour and 6 hour post UV stress recovery. DNA amplification of long mitochondrial (LM) DNA, short mitochondrial (SM) DNA, long nuclear (LN) DNA and short nuclear (SN) DNA. (B, D) Graphical representations of DNA damage experiments in panels A and C, respectively. X-axis represents number of lesions/10 kb and Y-axis represents time in hours.