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. 2013 Sep 5;9(9):e1003763. doi: 10.1371/journal.pgen.1003763

Figure 7. Conservation of human-chimpanzee differentially methylated sites among multiple somatic tissues.

Figure 7

Differentially methylated sites we identified using whole blood of human and chimpanzee were compared to a previous study that used the Illumina HumanMethylation27 DNA Analysis BeadChip to study liver, kidney and heart tissue in an independent population of humans and chimpanzees [19]. We found a significant trend for sites that are differentially methylated in blood to also show higher human-chimpanzee divergence in these other tissues (yellow box plot, n = 457) suggesting a conservation across other somatic tissues compared to non-differentially methylated sites in blood (grey box plot, n = 7,942).