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. 2013 Sep 5;7(9):e2424. doi: 10.1371/journal.pntd.0002424

Figure 4. PBMC cytokine secretion after stimulation measured by multiplex immunoassay.

Figure 4

IL-1β, IL-2, GM-CSF, IFN-γ, and TNF-α protein secretion by from control donors or acute or relapse brucellosis patients after stimulation with LPS, heat-killed B. melitensis (HKBM), or the heat-killed B. melitensis vaccine Rev1, as measured by multiplex immunoassay (asterisk indicates p≤0.05). Concentrations indicated by open circles were extrapolated beyond the assay standard curve and values in the red shaded zone fell outside the observable range (OOR).