Figure 5. CHIKV replication in C57BL/6 and Swiss albino mice.

C57BL/6 mice were infected with CHIKV (1×10⁶ PFU CHKV; 100 µl of 10⁷pfu/ml) by three different routes viz. intra venous, intra nasal and intra muscular. A) CHIKV copies were measured in hind limb muscle tissues on 0, 2, 4, 7, and 14 days p.i.. B) CHIKV RNA copies in hind limb muscle tissues of C57BL/6 mice on 1–14 days p.i. C) CHIKV RNA copies in serum of C57BL/6 mice on 1–14 days D) CHIKV RNA copies in serum of swiss albino mice.