Fig. 3.

Interstitial glucose (a, d), lactate (b, e) and pyruvate concentrations (c, f) in subcutaneous AT (a–c) and SM (d–f) during baseline and the three-step 6 h hyperinsulinaemic–euglycaemic clamp (8, 20, 40 mU m⁻² min⁻¹) in 11 obese men with NGT (black squares) compared with nine type 2 diabetic men (white squares). The response was compared using ANOVA. AT and SM glucose (a and d) curves and SM lactate (e) curves were significantly different between groups (p < 0.01). Values are means ± SEM. B, baseline