Figure 2.

Graphs showing mean time course data (n=7 per group) of T₂* signal change to 0.4 fraction of inspired oxygen (FiO₂) (A) or perfluorocarbon (PFC) +0.4 FiO₂ (B) in the four regions of interests (ROIs); blue shading indicates the period of oxygen challenge (OC) with 0.4 FiO₂. (C) Peak T₂* signal changes to 0.4 FiO₂ with and without prior administration of PFC in the four ROIs. Horizontal bars indicate means. *indicates significantly greater signal change in T₂*-defined penumbra (P) compared to all other ROIs. ^#indicates significantly enhanced T₂* response in the P to 40% oxygen following PFC when compared to 40% oxygen alone.